Colorado Mass Tort Attorneys – Burg Simpson

PPIs for Acid Reflux May Be Associated with Life-Threatening Complications

PPIs for Acid Reflux – Denver Mass Tort Attorney – Burg SimpsonProton pump inhibitors are a class of drugs used to treat heartburn, ulcers, acid reflux and other gastrointestinal issues. Some of the most popular drugs within this category include Prilosec, Nexium, and Prevacid. These heartburn drugs are frequently promoted by the manufacturers as effective and safe, leading many doctors to continue prescribing these medications. However, patients who take a proton pump inhibitor (PPI) to alleviate heartburn or acid reflux, may experience severe side effects. Recent studies concluded that taking a PPI may be associated with an increased risk for serious, chronic, even life-threatening side effects such as:

  • Chronic kidney disease
  • Acute kidney injury, also called “acute renal failure”
  • Kidney transplant
  • End-stage renal failure, also called “end-stage renal disease”
  • Interstitial nephritis (a type of inflammation in the kidneys)

How Do Proton Pump Inhibitors Work?

Proton pump inhibitors work by reducing the level of stomach acid produced by the glands in your stomach’s lining. By doing so, PPI’s minimize the symptoms of heartburn and pain caused if that stomach juice backs up into the esophagus. This also gives the esophagus appropriate time to heal.

These prescription and over-the-counter PPI medications may be associated with an increased risk of serious, life-threatening kidney problems:

  • Nexium (esomeprazole)
  • Nexium 24 HR (esomeprazole)
  • Prevacid (lansoprazole)
  • Prevacid 24 HR (lansoprazole)
  • Prilosec (omeprazole)
  • Prilosec OTC (omeprazole)
  • Zegerid (omeprazole with sodium bicarbonate)
  • Zegerid OTC (omeprazole with sodium bicarbonate)
  • Dexilant (dexlansoprazole)
  • Dexilant SoluTab (dexlansoprazole)
  • Protonix (pantoprazole)
  • AcipHex (rabeprazole)
  • AcipHex Sprinkle (rabeprazole)

Recent Studies Show a Connection Between PPI Use and Kidney Injuries

According to recently published studies, taking a PPI may increase an individual’s risk of developing chronic kidney disease, acute kidney injury or interstitial nephritis. Your kidneys filter waste products and extra fluid from the blood and remove them from your body through your urine. Chronic kidney disease, also called chronic kidney failure, occurs gradually as the kidneys lose their ability to function. As the kidneys lose their ability to function, waste products and excessive fluid can accumulate in the body. If the condition progresses, kidney dialysis or a kidney transplant may be required. Left untreated, or if treatment is unsuccessful, the condition can be fatal.

Acute kidney injury, or acute renal failure, occurs suddenly over several hours or days. The kidneys rapidly lose their ability to filter waste products, which may lead to excessively high levels of waste products and fluid imbalances in the body. Patients who suffer from acute kidney injury can also experience cardiovascular complications (such as heart failure, heart attack, arrhythmias or cardiac arrest) and lung complications, which can be fatal. Acute kidney injury can lead to chronic kidney disease and end-stage renal disease. Immediate treatment is necessary or the condition can be fatal.

Interstitial nephritis is another type of kidney disorder. This condition is characterized by inflammation in specific tissue in the kidneys, which interferes with how the kidneys function. In severe cases, the inflammation can lead to chronic kidney failure and cause permanent damage to the kidneys.

Short term use of proton pump inhibitors has not currently been linked to any catastrophic side effects. However, those patients who have been using the medication for some time may be at a high risk of serious bone fracture as well. The FDA recommends that no individual take more than three different 14-day treatment courses over a one-year period. In one recent study involving 135 patients over the age of 50, high doses of proton pump inhibitors taken over the course of 12 months increased the chances of that patient breaking his or her hip by more than two and a half times.

PPIs have been aggressively marketed to consumers. Research from the San Francisco Public Health Department shows that these drugs are often prescribed when patients may actually benefit more from diet and lifestyle changes.

PPI Manufacturers Do Not Warn of All Dangerous Side Effects of PPI Use

Although manufacturers of proton pump inhibitors provide information about potential side effects and contraindications, they do not warn about the severe, sometimes life-threatening risk of acute kidney injury or chronic kidney disease e associated with these medications.

While the U.S. Food and Drug Administration (FDA) has issued a number of safety warnings regarding proton pump inhibitors, such as warnings about PPI’s association with bone fractures, low magnesium levels, and a specific type of gastrointestinal inflammation caused by a particular bacteria, it has not specifically addressed the very real and dangerous possibility of irreparable kidney damage.

If you’ve suffered a kidney injury as a result of taking a Proton Pump Inhibitor medication, please call 303-792-5595 to speak with our Colorado mass tort attorneys. The case was was recently designed as a multi-district litigation (MDL) and assigned to the Hon. Claire C. Cecchi, United States District Court for the District of New Jersey. On August 23, 2017, Judge Cecchi appointed Burg Simpson shareholder Seth A. Katz to serve on the Plaintiffs’ Executive Committee.

Alan K. Simpson Supports Tax Reform – If It’s Paid For

 December 13, 2017

Alan K. Simpson Supports Tax Reform – If It’s Paid For

Burg Simpson co-founder Alan K. Simpson wants to make it clear that, like most Americans, he supports tax reform. Just not this tax reform. Simpson, in an op-ed drafted with fellow former senator Bob Kerrey and published in the Philadelphia Inquirer last week, argues that the House and Senate proposals under consideration right now include… Read more »

University of Denver Profiles Michael S. Burg

 December 12, 2017

University of Denver Profiles Michael S. Burg

The University of Denver’s Sturm College of Law profiled one of its more famous alumni, Burg Simpson founding shareholder Michael S. Burg. Michael, who earned his JD from Sturm in 1975, also was inducted into the Trial Lawyer Hall of Fame just last year. He’s the first DU grad to earn the honor. Michael discussed… Read more »

Alan K. Simpson Blasts Divisive Politics

 December 7, 2017

Alan K. Simpson Blasts Divisive Politics

Burg Simpson co-founder Alan K. Simpson’s civility in politics tour continued this week with a public forum at Montana State University Billings with former Senate colleague Max Baucus, a Montana Democrat. The two elder statesmen of upper Midwestern politics, both of whom entered the Senate in 1978, lamented the hostility that’s so prevalent in Washington,… Read more »

President’s Pick to Run CFPB Spells Disaster

 November 29, 2017

President’s Pick to Run CFPB Spells Disaster

Things keep getting worse with the Trump White House. The latest fiasco involves the Consumer Financial Protection Bureau (CFPB), where a pair of appointees showed up to work earlier this week – to do the same job. It’s an awkward situation made worse since President Trump’s appointee, Mick Mulvaney, already has a another job as… Read more »

Consumers Can Sue Banks – Colorado Mass Tort Lawyers – Burg Simpson

 July 17, 2017

Consumers Win Right to Sue Banks

In a regulatory environment that has lately favored big business over the average American consumer, the underdog got a rare win this week. The Consumer Financial Protection Bureau, an independent federal watchdog group, issued a rule on July 10 that will limit the ability of banks, credit card companies, and other financial institutions to force… Read more »

Device Recall - Dangerous Medical Devices Attorney – Burg Simpson

 April 24, 2017

What is a Medical Device Recall?

When a person undergoes a medical procedure involving the use of a medical device, that person trusts it’s safe and effective. Unfortunately, this isn’t always the case. When it becomes clear that a medical device is causing unexpected harm to consumers, a medical device manufacturer must take measures to address such serious problems. One such… Read more »

Reverse Shoulder- denver Mass tort lawyers - Burg Simpson

 February 17, 2017

Recall Alert: Comprehensive Reverse Shoulder Recalled by Zimmer Biomet

Zimmer Biomet has issued a Class I Recall of its Comprehensive Reverse Shoulder due to higher than reported fracture rates.  Zimmer Biomet issued the recall on December 15, 2016.  The Zimmer recall includes thousands of Comprehensive Reverse Shoulders.  The recalled devices were distributed between October 2008 and September 2015.  As part of the shoulder recall,… Read more »

Mike Burg Holds First Book Signing for Trial by Fire at Tattered Cover

 August 18, 2016

Mike Burg Holds First Book Signing for Trial by Fire at Tattered Cover

Last month at the Tattered Cover Book Store in Denver, Colorado, a crowd of over 100 were treated to an evening with Burg Simpson attorney and author, Mike Burg. Speaking about his new book, Trial By Fire: One Man’s Battle to End Corporate Greed and Save Lives, Mike discussed his childhood and his motivations that… Read more »

Ring of Fire: Even Republicans Are Disgusted by The Republican Party

 May 3, 2016

Ring of Fire: Even Republicans Are Disgusted by The Republican Party

A Ring of Fire first! Host Farron Cousins talks to former Senator Alan Simpson in a unique opportunity on Ring of Fire to speak with a Republican about the current state of the Republican Party.

CBS 4: Michael Burg Inducted to Trial Lawyer Hall of Fame

 April 28, 2016

CBS 4: Michael Burg Inducted to Trial Lawyer Hall of Fame

CBS 4 in Denver highlights Burg Simpson attorney Michael S. Burg’s induction into the Trial Lawyer Hall of Fame

Radio 850KOA: Michael Burg Inducted to Trial Lawyer Hall of Fame

 April 28, 2016

Radio 850KOA: Michael Burg Inducted to Trial Lawyer Hall of Fame

Denver’s Radio 850KOA ran a news story about Michael Burg’s induction into the Trial Lawyer Hall of Fame.

Burg Simpson Legal Minute: Civil Justice System

 April 21, 2016

Burg Simpson Legal Minute: Civil Justice System

Burg Simpson shareholder Calvin Tregre Jr. examines changes to the civil justice system, where limitations have been placed on monetary awards to seriously injured victims of corporate negligence. Are you protected?

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