Colorado Dangerous Drugs & Medical Devices

PPIs for Acid Reflux May Be Associated with Life-Threatening Complications – Mass Tort Attorney

PPIs for Acid Reflux – Denver Mass Tort Attorney – Burg SimpsonProton pump inhibitors are a class of drugs used to treat heartburn, ulcers, acid reflux and other gastrointestinal issues. Some of the most popular drugs within this category include Prilosec, Nexium, and Prevacid. These heartburn drugs are frequently promoted by the manufacturers as effective and safe, leading many doctors to continue prescribing these medications. However, patients who take a proton pump inhibitor (PPI) to alleviate heartburn or acid reflux, may experience severe side effects. Recent studies concluded that taking a PPI may be associated with an increased risk for serious, chronic, even life-threatening side effects such as:

  • Chronic kidney disease
  • Acute kidney injury, also called “acute renal failure”
  • Kidney transplant
  • End-stage renal failure, also called “end-stage renal disease”
  • Interstitial nephritis (a type of inflammation in the kidneys)

How Do Proton Pump Inhibitors Work?

Proton pump inhibitors work by reducing the level of stomach acid produced by the glands in your stomach’s lining. By doing so, PPI’s minimize the symptoms of heartburn and pain caused if that stomach juice backs up into the esophagus. This also gives the esophagus appropriate time to heal.

These prescription and over-the-counter PPI medications may be associated with an increased risk of serious, life-threatening kidney problems:

  • Nexium (esomeprazole)
  • Nexium 24 HR (esomeprazole)
  • Prevacid (lansoprazole)
  • Prevacid 24 HR (lansoprazole)
  • Prilosec (omeprazole)
  • Prilosec OTC (omeprazole)
  • Zegerid (omeprazole with sodium bicarbonate)
  • Zegerid OTC (omeprazole with sodium bicarbonate)
  • Dexilant (dexlansoprazole)
  • Dexilant SoluTab (dexlansoprazole)
  • Protonix (pantoprazole)
  • AcipHex (rabeprazole)
  • AcipHex Sprinkle (rabeprazole)

Recent Studies Show a Connection Between PPI Use and Kidney Injuries

According to recently published studies, taking a PPI may increase an individual’s risk of developing chronic kidney disease, acute kidney injury or interstitial nephritis. Your kidneys filter waste products and extra fluid from the blood and remove them from your body through your urine. Chronic kidney disease, also called chronic kidney failure, occurs gradually as the kidneys lose their ability to function. As the kidneys lose their ability to function, waste products and excess fluid can accumulate in the body. If the condition progresses, kidney dialysis or a kidney transplant may be required. Left untreated, or if treatment is unsuccessful, the condition can be fatal.

Acute kidney injury, or acute renal failure, occurs suddenly over several hours or days. The kidneys rapidly lose their ability to filter waste products, which may lead to excessively high levels of waste products and fluid imbalances in the body. Patients who suffer from acute kidney injury can also experience cardiovascular complications (such as heart failure, heart attack, arrhythmias or cardiac arrest) and lung complications, which can be fatal. Acute kidney injury can lead to chronic kidney disease and end-stage renal disease. Immediate treatment is necessary or the condition can be fatal.

Interstitial nephritis is another type of kidney disorder. This condition is characterized by inflammation in specific tissue in the kidneys, which interferes with how the kidneys function. In severe cases, the inflammation can lead to chronic kidney failure and cause permanent damage to the kidneys.

Short term use of proton pump inhibitors has not currently been linked to any catastrophic side effects. However, those patients who have been using the medication for some time may be at high risk of serious bone fracture as well. The FDA recommends that no individual take more than three different 14-day treatment courses over a one-year period. In one recent study involving 135 patients over the age of 50, high doses of proton pump inhibitors taken over the course of 12 months increased the chances of that patient breaking his or her hip by more than two and a half times.

PPIs have been aggressively marketed to consumers. Research from the San Francisco Public Health Department shows that these drugs are often prescribed when patients may actually benefit more from diet and lifestyle changes.

PPI Manufacturers Do Not Warn of All Dangerous Side Effects of PPI Use

Although manufacturers of proton pump inhibitors provide information about potential side effects and contraindications, they do not warn about the severe, sometimes life-threatening risk of acute kidney injury or chronic kidney disease e associated with these medications.

While the U.S. Food and Drug Administration (FDA) has issued a number of safety warnings regarding proton pump inhibitors, such as warnings about PPI’s association with bone fractures, low magnesium levels, and a specific type of gastrointestinal inflammation caused by a particular bacteria, it has not specifically addressed the very real and dangerous possibility of irreparable kidney damage.

If you have suffered a kidney injury as a result of taking a Proton Pump Inhibitor medication, please call 303-792-5595 to speak with our Colorado mass tort attorneys. The case was recently designed as a multi-district litigation (MDL) and assigned to the Hon. Claire C. Cecchi, United States District Court for the District of New Jersey. On August 23, 2017, Judge Cecchi appointed Burg Simpson shareholder Seth A. Katz to serve on the Plaintiffs’ Executive Committee.

 November 19, 2019

Jury Awards a $58 Million Verdict in the “Body Parts Case”

Jury Awards a $58 Million Verdict in the “Body Parts Case”: Ten of 21 plaintiffs who sued a now-shuttered Phoenix body donation company will be awarded $58 million. Burg Simpson shareholders Michael S. Burg, David K. TeSelle, Holly B. Kammerer, and their team of lawyers and legal professionals, recently brought justice for their clients when a Maricopa County… Read more »

 November 8, 2019

Injured? Med Pay Benefits May Be Available

Injured? Med Pay Benefits May Be Available Medical payment insurance, or “med pay” for short, is a type of insurance that provides for the payment of an injured person’s medical bills- up to a certain amount- if there has been an accident, regardless of who was at fault. Although one can purchase med-pay insurance as… Read more »

 November 6, 2019

BURG SIMPSON: “BEST LAW FIRM 2020” RECIPIENT

BURG SIMPSON: “BEST LAW FIRM 2020” RECIPIENT ABOUT THE “BEST LAW FIRMS” LIST U.S. News & World Report and Best Lawyers cooperatively released its tenth annual list of “Best Law Firms” rankings. Burg Simpson was included as a #1 National Ranked law firm for Mass Tort Litigation & Class Action suits. Firms included in the 2020 Edition of… Read more »

 November 5, 2019

Channel 7 Interviews Burg Simpson About the “Human Body Part Case”

THE HUMAN BODY PART CASE Channel 7 interviews Burg Simpson About the “Human Body Part Case”: Michael S. Burg and David K. TeSelle, trial lawyers at the Denver-based firm of Burg Simpson Eldredge Hersh & Jardine, were recently interviewed by Denver’s Channel 7 about a once-secret black-market industry that involves the selling of human body… Read more »

Holding Pharmaceutical Companies Responsible – Mass Tort | Dangerous Drugs & Medical Devices

 November 12, 2019

Holding Pharmaceutical Companies Responsible – Mass Tort | Dangerous Drugs & Medical Devices

Burg Simpson’s Colorado mass tort attorneys have represented thousands of people who have suffered serious side effects after taking dangerous medications or those who have been hurt by a defective product.  If you have suffered injuries related to a defective drug or medical device, contact the Burg Simpson mass tort team at 303-790-2525.

bike-crash-safety

 November 8, 2019

Bike Crash Safety Video – Burg Simpson Personal Injury

The personal injury attorneys at Burg Simpson help fellow bicycle enthusiasts understand how to protect their rights after a bike crash and stay safe on the roads. If you have been hurt in a bike crash and need help, reach out to us today by calling our office or filling out our online free case… Read more »

7th Annual Jeremy Bitner Memorial Run for the Fallen Officers Fund

 July 1, 2019

7th Annual Jeremy Bitner Memorial Run for the Fallen Officers Fund

The Jeremy Bitner Foundation was established in honor of Englewood Police Detective Jeremy Bitner. Detective Bitner lost his life in the line of duty on May 28, 2012, after being struck and killed by a vehicle while performing a traffic stop. Jeremy served the Englewood Police Department for 8 years and during that time was assigned… Read more »

The 2019 Burg Simpson Scholarship Awards Dinner

 May 7, 2019

The 2019 Burg Simpson Scholarship Awards Dinner

The 2019 Burg Simpson Scholarship Awards Dinner was held at Maggiano’s on April 25th to recognize the ten winners of the firm’s annual scholarship competition. The firm’s founder Michael Burg, and shareholders Peter Burg and Stephan Marsh presented awards to the 2019 winners! This year’s recipients included Ms. Madison Frotten, Mr. Dale Kim, Ms. McKenna… Read more »

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