Colorado Dangerous Drugs & Medical Devices

PPIs for Acid Reflux May Be Associated with Life-Threatening Complications – Mass Tort Attorney

PPIs for Acid Reflux – Denver Mass Tort Attorney – Burg SimpsonProton pump inhibitors are a class of drugs used to treat heartburn, ulcers, acid reflux and other gastrointestinal issues. Some of the most popular drugs within this category include Prilosec, Nexium, and Prevacid. These heartburn drugs are frequently promoted by the manufacturers as effective and safe, leading many doctors to continue prescribing these medications. However, patients who take a proton pump inhibitor (PPI) to alleviate heartburn or acid reflux, may experience severe side effects. Recent studies concluded that taking a PPI may be associated with an increased risk for serious, chronic, even life-threatening side effects such as:

  • Chronic kidney disease
  • Acute kidney injury, also called “acute renal failure”
  • Kidney transplant
  • End-stage renal failure, also called “end-stage renal disease”
  • Interstitial nephritis (a type of inflammation in the kidneys)

How Do Proton Pump Inhibitors Work?

Proton pump inhibitors work by reducing the level of stomach acid produced by the glands in your stomach’s lining. By doing so, PPI’s minimize the symptoms of heartburn and pain caused if that stomach juice backs up into the esophagus. This also gives the esophagus appropriate time to heal.

These prescription and over-the-counter PPI medications may be associated with an increased risk of serious, life-threatening kidney problems:

  • Nexium (esomeprazole)
  • Nexium 24 HR (esomeprazole)
  • Prevacid (lansoprazole)
  • Prevacid 24 HR (lansoprazole)
  • Prilosec (omeprazole)
  • Prilosec OTC (omeprazole)
  • Zegerid (omeprazole with sodium bicarbonate)
  • Zegerid OTC (omeprazole with sodium bicarbonate)
  • Dexilant (dexlansoprazole)
  • Dexilant SoluTab (dexlansoprazole)
  • Protonix (pantoprazole)
  • AcipHex (rabeprazole)
  • AcipHex Sprinkle (rabeprazole)

Recent Studies Show a Connection Between PPI Use and Kidney Injuries

According to recently published studies, taking a PPI may increase an individual’s risk of developing chronic kidney disease, acute kidney injury or interstitial nephritis. Your kidneys filter waste products and extra fluid from the blood and remove them from your body through your urine. Chronic kidney disease, also called chronic kidney failure, occurs gradually as the kidneys lose their ability to function. As the kidneys lose their ability to function, waste products and excessive fluid can accumulate in the body. If the condition progresses, kidney dialysis or a kidney transplant may be required. Left untreated, or if treatment is unsuccessful, the condition can be fatal.

Acute kidney injury, or acute renal failure, occurs suddenly over several hours or days. The kidneys rapidly lose their ability to filter waste products, which may lead to excessively high levels of waste products and fluid imbalances in the body. Patients who suffer from acute kidney injury can also experience cardiovascular complications (such as heart failure, heart attack, arrhythmias or cardiac arrest) and lung complications, which can be fatal. Acute kidney injury can lead to chronic kidney disease and end-stage renal disease. Immediate treatment is necessary or the condition can be fatal.

Interstitial nephritis is another type of kidney disorder. This condition is characterized by inflammation in specific tissue in the kidneys, which interferes with how the kidneys function. In severe cases, the inflammation can lead to chronic kidney failure and cause permanent damage to the kidneys.

Short term use of proton pump inhibitors has not currently been linked to any catastrophic side effects. However, those patients who have been using the medication for some time may be at a high risk of serious bone fracture as well. The FDA recommends that no individual take more than three different 14-day treatment courses over a one-year period. In one recent study involving 135 patients over the age of 50, high doses of proton pump inhibitors taken over the course of 12 months increased the chances of that patient breaking his or her hip by more than two and a half times.

PPIs have been aggressively marketed to consumers. Research from the San Francisco Public Health Department shows that these drugs are often prescribed when patients may actually benefit more from diet and lifestyle changes.

PPI Manufacturers Do Not Warn of All Dangerous Side Effects of PPI Use

Although manufacturers of proton pump inhibitors provide information about potential side effects and contraindications, they do not warn about the severe, sometimes life-threatening risk of acute kidney injury or chronic kidney disease e associated with these medications.

While the U.S. Food and Drug Administration (FDA) has issued a number of safety warnings regarding proton pump inhibitors, such as warnings about PPI’s association with bone fractures, low magnesium levels, and a specific type of gastrointestinal inflammation caused by a particular bacteria, it has not specifically addressed the very real and dangerous possibility of irreparable kidney damage.

If you’ve suffered a kidney injury as a result of taking a Proton Pump Inhibitor medication, please call 303-792-5595 to speak with our Colorado mass tort attorneys. The case was was recently designed as a multi-district litigation (MDL) and assigned to the Hon. Claire C. Cecchi, United States District Court for the District of New Jersey. On August 23, 2017, Judge Cecchi appointed Burg Simpson shareholder Seth A. Katz to serve on the Plaintiffs’ Executive Committee.

Janet G. Abaray Named One of the Top 15 Businesswomen in Ohio

 May 17, 2018

Janet G. Abaray Named One of the Top 15 Businesswomen in Ohio

Burg Simpson attorneys have always been leaders in their communities. Shareholder Janet G. Abaray is no different. That’s why the Ohio Diversity Conference and the National Women’s Conference chose to honor Janet as one of the Top 15 Businesswomen in Ohio at the 2018 National Women’s Conference last week. This award honors “outstanding leaders and… Read more »

David P. Hersh Speaks at ACBA Event

 May 7, 2018

David P. Hersh Speaks at ACBA Event

Burg Simpson shareholder David P. Hersh was a featured speaker at a recent Arapahoe County Bar Association (ACBA) event in Napa, California. The session, part of this year’s Spring 2018 CLE event, was called “The Practical Implications for Implementing the Recommendations of the ABA National Task Force on Lawyer Well-Being.” David covered “the findings and… Read more »

Stephen J. Burg Speaks at Colorado Trial Lawyers Seminar

 April 25, 2018

Stephen J. Burg Speaks at Colorado Trial Lawyers Seminar

Burg Simpson shareholder Stephen J. Burg took part in a day-long continuing education seminar sponsored by the Colorado Trial Lawyers Association. The event, “In Search of a New Paradigm: Recalibrating the Moral Compass of an Industry to Serve Future Generations,” took place at the Embassy Suites Denver Downtown Convention Center in Denver. Stephen’s segment, presented… Read more »

Burg Simpson Scholarship Competition Winners Honored at Annual Dinner

 April 24, 2018

Burg Simpson Scholarship Competition Winners Honored at Annual Dinner

Our 2017-2018 Burg Simpson Scholarship Competition recipients were honored this past Thursday at our annual Scholarship Banquet. This year’s winners included: Elise Hegarty (Faith Christian Academy) Diana Barila (Longmont High School) Kelly Franson (D’Evelyn Jr./Sr. High School) Emilio D. Gómez (Regis Jesuit High School) Lucy Kane (Valor Christian High School) Andra Metcalfe (Mountain Vista High… Read more »

Denver Personal Injury Attorney – TBI & Dementia – Colorado Burg Simpson

 May 23, 2018

Research Confirms Link Between TBIs and Dementia

There’s been research in the past to suggest that even mild traumatic brain injuries can increase someone’s risk of developing a neurodegenerative disease, but a new study – published earlier this month – reinforces these findings. The study, “Association of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in U.S. Military… Read more »

Burg Simpson Denver - Colorado Supreme Court

 May 21, 2018

Colorado Supreme Court Decides Insurance Companies Cannot Delay Payment of Benefits Owed When The Payment Of Other Benefits Is Disputed

In an important victory for consumers, earlier today the Colorado Supreme Court unanimously decided that insurance companies cannot delay paying benefits owed under a policy just because the payment of other benefits is disputed. The case is State Farm vs. Fisher.  Mr. Fisher had several policies in place with State Farm with underinsured motorists (“UIM”)… Read more »

Bad Flu Season – Medical Malpractice Attorney Denver – Colorado Burg Simpson

 May 14, 2018

A Bad Flu Season Can Get Worse

The year’s flu season has been historically severe. All but two states – Hawaii and Oregon – continued to report pervasive flu activity. More than 40 states have reported unusually high flu activity. Tragically, the flu has claimed the lives of 165 children this year — and it’s far from over. The U.S. Centers for… Read more »

OHSA Standard Limits Worker Exposure to Silica - Construction Defect Law Firm - Burg Simpson

 May 2, 2018

Community Managers, Homeowner Associations, and Homeowners Beware – New OHSA Standard Limits Worker Exposure to Silica

More than 2 million workers are exposed to crystalline silica every year on the job, according to the Occupational Safety and Health Administration, most of whom work in general construction. The other 10 percent of exposed workers are in either the general industry, maritime, or fracking trades. Crystalline silica is an everyday mineral found in… Read more »

Ring of Fire: Even Republicans Are Disgusted by The Republican Party

 May 3, 2016

Ring of Fire: Even Republicans Are Disgusted by The Republican Party

A Ring of Fire first! Host Farron Cousins talks to former Senator Alan Simpson in a unique opportunity on Ring of Fire to speak with a Republican about the current state of the Republican Party.

CBS 4: Michael Burg Inducted to Trial Lawyer Hall of Fame

 April 28, 2016

CBS 4: Michael Burg Inducted to Trial Lawyer Hall of Fame

CBS 4 in Denver highlights Burg Simpson attorney Michael S. Burg’s induction into the Trial Lawyer Hall of Fame

Radio 850KOA: Michael Burg Inducted to Trial Lawyer Hall of Fame

 April 28, 2016

Radio 850KOA: Michael Burg Inducted to Trial Lawyer Hall of Fame

Denver’s Radio 850KOA ran a news story about Michael Burg’s induction into the Trial Lawyer Hall of Fame.

Ring of Fire: The Unseen Economic Crisis

 February 29, 2016

Ring of Fire: The Unseen Economic Crisis

Ring of Fire host Farron Cousins talks with Michael Burg about taxes and the government’s resistance to upgrade America’s infrastructure.

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