Colorado Dangerous Drugs & Medical Devices

Actos® – Denver Dangerous Drug Attorneys

Actos Drug - Colorado Mass Tort Lawyers - Colorado Burg Simpson Burg Simpson is not currently pursuing new Actos® cases.

In April 2015, Actos® manufacturer Takeda Pharmaceuticals agreed to a $2.4 billion settlement to resolve the claims of thousands of patients who took Actos® and developed bladder cancer. The agreement requires that at least 95% of eligible claimants agree to the terms of the settlement, which will compensate plaintiffs based on their age, the extent of their bladder cancer injury, the cumulative dosage of Actos® used, and history of certain risk factors for bladder cancer, including smoking. This is one of the largest pharmaceutical industry settlements in history. Read more about the Actos® settlement here.

The United States Food & Drug Administration (FDA) and the European Medicines Agency (EMA) have issued urgent safety alerts regarding the Type-2 Diabetes drug Actos® (pioglitazone).
On June 15, 2011, the FDA issued an urgent health warning to doctors/patients that Actos® may increase the risk of bladder cancer by up to 40%. Long-term users of Actos and those exposed to higher cumulative doses are among the groups at the greatest risk.

The FDA now requires that these recent findings and risks be included in the Warnings and Precautions section of the label for Actos® and other pioglitazone-containing medicines. In the meantime, the FDA has chosen not to issue an Actos® recall and the drug remains available to consumers in the United States despite these alarming statistics.

Symptoms of Actos®-related Bladder Cancer May Include:

• Blood in urine
• Change in urine color
• Frequent urination
• Painful urination
• Urinary tract infection

Actos® And Bladder Cancer: History

Actos® originally received FDA clearance in 1999. At the FDA’s request, Takeda Pharmaceuticals agreed to undertake a 10-year epidemiological post-market study in 2002, investigating the questions raised about Actos® and bladder cancer. An interim analysis of the data produced from the study showed an increased likelihood of bladder cancer developing in patients who took Actos® for the longest periods of time and at the highest cumulative doses. The FDA has informed the public that “… use of the diabetes medication ACTOS (pioglitazone) for more than one year may be associated with an increased risk of bladder cancer.” According to the FDA’s warning, “Compared to never being exposed to pioglitazone, a duration of pioglitazone therapy longer than 12 months was associated with a 40% increase in risk.

No U.S. Actos® Recall Despite Health Risks

The FDA now requires that information about this increased risk be added to the Warnings and Precautions section of the label for Actos® and other pioglitazone-containing medicines. At this time, the Agency has stopped short of issuing an Actos® recall. The FDA “stresses that there is no definitive proof that Actos® causes bladder cancer and that patients who are currently taking it should continue to do so unless otherwise advised by their healthcare provider.”

Actos® And Type-2 Diabetes

• Actos ® (pioglitazone) is manufactured by the Japanese drug company Takeda, and is co-marketed in the United States by Eli Lilly Pharmaceuticals.
• Actos® is an oral medication used to treat Type-2 diabetes in patients whose condition is not adequately controlled by diet and exercise alone.
• More than 2.3 million people were prescribed Actos® in 2010.
• Actos® belongs to a family of drugs known as Thiazolidinedione (TDZ), which are drugs used to lower blood sugar levels and increases the body’s sensitivity to insulin.
• The active ingredient in Actos® (pioglitazone) is also used in combination with other Type-2 diabetes therapies in other medicines such as Actoplus met®, Actoplus met® XR and Duetact®.
• Actos® became the world’s most popular Type-2 diabetes medicine in 2007 after medical studies linked Avandia , a similar drug produced by GlaxoSmithKline, with a 40% increased risk of a heart attack.
• Approximately 20 Million Americans suffer from Type-2 Diabetes.
• According to the National Cancer Institute, there were more than 70,00 cases of bladder cancer in the U.S. in 2010, resulting in 14,680 deaths.

Powerful Firm. Personal Touch.
With our resources, we can provide the level of service that smaller firms often cannot, while still retaining the personal touch that you deserve. Our close relationships with many other national law firms and expert consultants around the country means you also have a national team of lawyers and experts on your side.

Why choose the Burg Simpson law firm?
• 60+ lawyers
• 10,000+ clients
• Federal Court appointments as Lead Counsel in several Multi-District Litigation cases
• #1 Products Liability Law Firm in the U.S. (Martindale-Hubbell)
• Nationwide representation
• A 40-year history of success

trophies

 February 13, 2020

Burg Simpson E-News: February 2020

Join Our Email List Complex Business and Commercial Litigation, Construction Defects, Dangerous Drugs & Medical Devices, Mass Tort, Class Action, Medical Malpractice, Personal Injury, and Workers’ Compensation FEBRUARY 2020 E-NEWS GOOD LAWYERS 5280 Magazine Recognizes Denver’s Top Lawyers for 2020 Burg Simpson Eldredge Hersh & Jardine is pleased to announce that Michael S. Burg , Peter W…. Read more »

 February 13, 2020

National Trial Lawyers Announces Top Lawyers for 2020!

National Trial Lawyers Announces the Top Lawyers for 2020! Burg Simpson is pleased to announce that the National Trial Lawyers Association has selected the Top 100 Attorneys and the Top 40 Under 40 Attorneys for 2020! The National Trial Lawyers Association is an invitation-only organization composed of the premier trial lawyers from each state or region… Read more »

 February 12, 2020

Mediation vs. Arbitration: Resolving Your Commercial Dispute

Mediation vs. Arbitration: Resolving Your Commercial Dispute Most commercial contracts have a provision stating that the parties will mediate disputes before taking the issue to arbitration or trial.  For those seeking to resolve a commercial dispute, it is important to know that litigation is typically expensive, time-consuming, public, and unpredictable. A trial’s outcome is always uncertain… Read more »

 February 11, 2020

Short-Term Healthcare Insurance & the Institutionalization of Post-Claims Underwriting

Jessica L. Derakhshanian and Shane C. Fulton, trial lawyers with Burg Simpson Eldredge Hersh & Jardine, recently published an article in the January edition of The Colorado Lawyer entitled Short-Term Healthcare Insurance and the Institutionalization of Post-Claims Underwriting. The article provides a review of short-term health insurance regulation over the last decade and analyzes the… Read more »

david-hersh-case-settlement

 December 9, 2019

Settling Commercial Litigation Cases

An out-of-court settlement is a legally-binding agreement between the parties to a lawsuit that effectively puts an end to the legal matter. A settlement resolves all disputes inherent in the lawsuit, and results in dismissal of the claims filed in court.  Sometimes a settlement will contain a requirement that other court orders be entered effectuating… Read more »

Holding Pharmaceutical Companies Responsible – Mass Tort | Dangerous Drugs & Medical Devices

 November 12, 2019

Holding Pharmaceutical Companies Responsible – Mass Tort | Dangerous Drugs & Medical Devices

Burg Simpson’s Colorado mass tort attorneys have represented thousands of people who have suffered serious side effects after taking dangerous medications or those who have been hurt by a defective product.  If you have suffered injuries related to a defective drug or medical device, contact the Burg Simpson mass tort team at 303-790-2525.

bike-crash-safety

 November 8, 2019

Bike Crash Safety Video – Burg Simpson Personal Injury

The personal injury attorneys at Burg Simpson help fellow bicycle enthusiasts understand how to protect their rights after a bike crash and stay safe on the roads. If you have been hurt in a bike crash and need help, reach out to us today by calling our office or filling out our online free case… Read more »

7th Annual Jeremy Bitner Memorial Run for the Fallen Officers Fund

 July 1, 2019

7th Annual Jeremy Bitner Memorial Run for the Fallen Officers Fund

The Jeremy Bitner Foundation was established in honor of Englewood Police Detective Jeremy Bitner. Detective Bitner lost his life in the line of duty on May 28, 2012, after being struck and killed by a vehicle while performing a traffic stop. Jeremy served the Englewood Police Department for 8 years and during that time was assigned… Read more »

Top 100 National Trial Lawyers Legal 500 Best Lawyers in America Super Lawyers US News 2014 Top 25 Most Influential Lawyers