SSRI Antidepressants & Birth Defects

Paxil® Side Effects

Controversy continues to surround the antidepressant drugs Paxil®, Paxil CR®, Pexeva® and its generic equivalent paroxetine hydrochloride. Manufactured by GlaxoSmithKline (GSK), Paxil® is a selective serotonin reuptake inhibitor (SSRI), widely prescribed for the treatment of depression, generalized anxiety disorder, social anxiety disorder, panic disorder, and obsessive compulsive disorder (OCD). Since its approval for use in the United States, a number of potentially life-threatening side effects have been linked to Paxil®, including an increased risk of birth defects in pregnant mothers as well as severe withdrawal symptoms in patients who stop taking the drug.  The most serious of which are birth defects in children born to mothers who took Paxil® during pregnancy.

Paxil® linked to birth defects

Recent medical studies have revealed that expectant mothers prescribed Paxil® are at a higher risk of giving birth to a baby with a birth defect than women taking other forms of antidepressant. Specifically, experts believe that fetuses exposed to Paxil® during the first trimester are at a much higher risk of developing ventricular septal (hole in the heart) and other cardiovascular defects. In addition research also points to an increased chance of developing the potentially fatal condition – persistent pulmonary hypertension.

Cardiovascular birth defects associated with Paxil®

  • Hypoplastic Left Heart
  • Pulmonary Atresia
  • Tricuspic Atresia
  • Transposition of the Great Vessels
  • Pulmonary Stenosis
  • Coarctation of the Aorta
  • Tetralogy of Fallot
  • Double Outlet Right Ventricle
  • Persistent Truncus Arteriosus
  • Interruption of the Aorta
  • Double Inlet Left Ventricle
  • Double Aortic Arch

In 2005, the FDA determined that “exposure to Paxil in the first trimester of pregnancy may increase the risk for congenital malformations, particularly cardiac malformations.”  The FDA also requested, GSK change Paxil’s pregnancy category from C to D and add further Warnings to the prescribing information issued with the drug. Yet despite these warnings and the obvious links to a variety of life-threatening illnesses, both Paxil® and paroxetine remain on the market.

If you or your child has been injured as a result of exposure to Paxil® or paroxetine, Burg Simpson’s award-winning dangerous drug lawyers would be happy to review your records to determine whether you have a viable case against GlaxoSmithKline or any other manufacturer. Call toll-free 1-888-895-2080 or email us to schedule a free consultation today.

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 February 13, 2020

Burg Simpson E-News: February 2020

Join Our Email List Complex Business and Commercial Litigation, Construction Defects, Dangerous Drugs & Medical Devices, Mass Tort, Class Action, Medical Malpractice, Personal Injury, and Workers’ Compensation FEBRUARY 2020 E-NEWS GOOD LAWYERS 5280 Magazine Recognizes Denver’s Top Lawyers for 2020 Burg Simpson Eldredge Hersh & Jardine is pleased to announce that Michael S. Burg , Peter W…. Read more »

 February 13, 2020

National Trial Lawyers Announces Top Lawyers for 2020!

National Trial Lawyers Announces the Top Lawyers for 2020! Burg Simpson is pleased to announce that the National Trial Lawyers Association has selected the Top 100 Attorneys and the Top 40 Under 40 Attorneys for 2020! The National Trial Lawyers Association is an invitation-only organization composed of the premier trial lawyers from each state or region… Read more »

 February 12, 2020

Mediation vs. Arbitration: Resolving Your Commercial Dispute

Mediation vs. Arbitration: Resolving Your Commercial Dispute Most commercial contracts have a provision stating that the parties will mediate disputes before taking the issue to arbitration or trial.  For those seeking to resolve a commercial dispute, it is important to know that litigation is typically expensive, time-consuming, public, and unpredictable. A trial’s outcome is always uncertain… Read more »

 February 11, 2020

Short-Term Healthcare Insurance & the Institutionalization of Post-Claims Underwriting

Jessica L. Derakhshanian and Shane C. Fulton, trial lawyers with Burg Simpson Eldredge Hersh & Jardine, recently published an article in the January edition of The Colorado Lawyer entitled Short-Term Healthcare Insurance and the Institutionalization of Post-Claims Underwriting. The article provides a review of short-term health insurance regulation over the last decade and analyzes the… Read more »


 December 9, 2019

Settling Commercial Litigation Cases

An out-of-court settlement is a legally-binding agreement between the parties to a lawsuit that effectively puts an end to the legal matter. A settlement resolves all disputes inherent in the lawsuit, and results in dismissal of the claims filed in court.  Sometimes a settlement will contain a requirement that other court orders be entered effectuating… Read more »

Holding Pharmaceutical Companies Responsible – Mass Tort | Dangerous Drugs & Medical Devices

 November 12, 2019

Holding Pharmaceutical Companies Responsible – Mass Tort | Dangerous Drugs & Medical Devices

Burg Simpson’s Colorado mass tort attorneys have represented thousands of people who have suffered serious side effects after taking dangerous medications or those who have been hurt by a defective product.  If you have suffered injuries related to a defective drug or medical device, contact the Burg Simpson mass tort team at 303-790-2525.


 November 8, 2019

Bike Crash Safety Video – Burg Simpson Personal Injury

The personal injury attorneys at Burg Simpson help fellow bicycle enthusiasts understand how to protect their rights after a bike crash and stay safe on the roads. If you have been hurt in a bike crash and need help, reach out to us today by calling our office or filling out our online free case… Read more »

7th Annual Jeremy Bitner Memorial Run for the Fallen Officers Fund

 July 1, 2019

7th Annual Jeremy Bitner Memorial Run for the Fallen Officers Fund

The Jeremy Bitner Foundation was established in honor of Englewood Police Detective Jeremy Bitner. Detective Bitner lost his life in the line of duty on May 28, 2012, after being struck and killed by a vehicle while performing a traffic stop. Jeremy served the Englewood Police Department for 8 years and during that time was assigned… Read more »

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