SSRI Antidepressants & Birth Defects

Paxil® Side Effects

Controversy continues to surround the antidepressant drugs Paxil®, Paxil CR®, Pexeva® and its generic equivalent paroxetine hydrochloride. Manufactured by GlaxoSmithKline (GSK), Paxil® is a selective serotonin reuptake inhibitor (SSRI), widely prescribed for the treatment of depression, generalized anxiety disorder, social anxiety disorder, panic disorder, and obsessive compulsive disorder (OCD). Since its approval for use in the United States, a number of potentially life-threatening side effects have been linked to Paxil®, including an increased risk of birth defects in pregnant mothers as well as severe withdrawal symptoms in patients who stop taking the drug.  The most serious of which are birth defects in children born to mothers who took Paxil® during pregnancy.

Paxil® linked to birth defects

Recent medical studies have revealed that expectant mothers prescribed Paxil® are at a higher risk of giving birth to a baby with a birth defect than women taking other forms of antidepressant. Specifically, experts believe that fetuses exposed to Paxil® during the first trimester are at a much higher risk of developing ventricular septal (hole in the heart) and other cardiovascular defects. In addition research also points to an increased chance of developing the potentially fatal condition – persistent pulmonary hypertension.

Cardiovascular birth defects associated with Paxil®

  • Hypoplastic Left Heart
  • Pulmonary Atresia
  • Tricuspic Atresia
  • Transposition of the Great Vessels
  • Pulmonary Stenosis
  • Coarctation of the Aorta
  • Tetralogy of Fallot
  • Double Outlet Right Ventricle
  • Persistent Truncus Arteriosus
  • Interruption of the Aorta
  • Double Inlet Left Ventricle
  • Double Aortic Arch

In 2005, the FDA determined that “exposure to Paxil in the first trimester of pregnancy may increase the risk for congenital malformations, particularly cardiac malformations.”  The FDA also requested, GSK change Paxil’s pregnancy category from C to D and add further Warnings to the prescribing information issued with the drug. Yet despite these warnings and the obvious links to a variety of life-threatening illnesses, both Paxil® and paroxetine remain on the market.

If you or your child has been injured as a result of exposure to Paxil® or paroxetine, Burg Simpson’s award-winning dangerous drug lawyers would be happy to review your records to determine whether you have a viable case against GlaxoSmithKline or any other manufacturer. Call toll-free 1-888-895-2080 or email us to schedule a free consultation today.


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 September 16, 2020

Four Teen Victims Seek $16 Million in Arizona Child Abuse Case

A team of Burg Simpson attorneys including Scott Eldredge, Seth Katz, Ty Taber, Paul Friedman, and Christopher Post along with Tucson-based victims’ rights attorney, Lynne Cadigan, is representing four adoptive children who are named as victims in $16 million child abuse cases filed in Arizona. The children allege they were subjected to aggravated assault and… Read more »

 September 8, 2020

Former Burg Simpson Scholarship Winner is Using Her Funds Wisely!

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 September 3, 2020

September 2020 E-News

Congratulations to Our Best Lawyers in America® Forty-seven Burg Simpson attorneys have been recognized in the 2021 edition of Best Lawyers in America ®. (33 “Best Lawyers” and 14 “Ones to Watch.”) See the list of Burg Simpson attorneys selected to the 2021 Best Lawyers in America ® here. Three Burg Simpson Lawyers Also Named Best… Read more »

 August 27, 2020

Burg Simpson’s Colorado Scholarship Competition 2020-2021

Burg Simpson has always recognized the importance of access to a strong education. Starting in 2012, we launched the Burg Simpson Scholarship Competition. Each year, Colorado high school seniors are encouraged to write and submit a 1,500 word essay on the importance of the civil jury system as the guardian of American rights and liberties… Read more »

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 June 19, 2020

David Hersh: COVID-19 and Loss of Business Income

Shareholder David Hersh Discusses COVID-19 and Loss of Business Income  David P. Hersh is a shareholder and co-practice group leader with  Burg Simpson’s business and commercial litigation department.  “I am David Hersh, Co-leader of the Commercial Litigation Department at Burg Simpson. Business owners across the country have suffered from the loss of business income as… Read more »

David TeSelle Discusses Qui Tam Lawsuits

 June 18, 2020

David TeSelle Discusses Qui Tam Lawsuits

David K. TeSelle is a trial lawyer and co-practice group leader with  Burg Simpson’s business and commercial litigation department.  “Do you have confidential information about a company who is cheating the state or federal government out of money, leaving the American taxpayer holding the bag? If so, there is something you can do about it,… Read more »

 June 16, 2020

Shareholder Jacob Burg Discusses Burg Simpson’s Commitment to Pro Bono Work

Jake Burg is a shareholder and a trial lawyer with  Burg Simpson’s personal injury department. “Since the firm’s inception in 1976, Burg Simpson has been committed to providing pro bono legal services to heroes who have dedicated themselves to serving others in times of great need. As an attorney with Burg Simpson, I was proud to… Read more »

Denver, CO – Two Injured in Motorcycle Accident on I-25 (CanAm Highway)

 June 15, 2020

Injured in a Motorcycle Crash? Call Burg Simpson Now

Injured in a Motorcycle Crash? Call Burg Simpson Now Shareholder Stephen J. Burg is a trial lawyer and the practice group leader of the firm’s personal injury department. If you, or someone you know, has been injured in a motorcycle crash, you need someone to be on your side. Insurance companies make huge profits by… Read more »

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